This queen stage starts from Moena which has been stage town six times and goes across the Dolomites taking in 5 consecutive categorised climbs, with not even a single flat stretch in between: Passo Pordoi (2016 KOM Damiano Cunego), Passo Valparola, Passo Gardena, Passo Pinei and Pontives (final climb). The stage features a remarkable rise and drop of a little less than 4,000 m in 137 km, with average gradients of approx. 7% and topping out at 15%. The roads are always moderately wide and well surfaced. The stage arrives in Ortisei, already arrival of the Giro in 1940 and 2005.
The Pontives categorised summit (4 km before the finish) marks the slope change in the closing climb. Next on the route are a false-flat uphill drag, up to 1,500 m before the finish, and a steep stretch up to 500 m before the finish, with gradients topping out at 13%. The stage course then turns right and takes a short descent on setts-paved road, up to 150 m from the finish, where the road levels out. The finish line sits on 5.5-m wide asphalt road.